This lefty thing only exists with guitarists and drummers, because it's easy to rearrange a drum set or flip a guitar over and reverse the strings. But you don't see backwards pianos, left pointing flutes or mirror image trombones, and no one seems to ever have a problem with this.
My daughter is a natural lefty from day one. When she wanted a uke I could have reversed the strings for her, but thought that maybe I'd put it in her hands as a righty first and see how she does. And it worked.
