For a long time I used an Ampeg VT-22 cab, which, when the vintage drivers blew, I loaded with more modern Eminence drivers (I forget which ones, this was around 1994).
It sounded great up close, I loved recording it, but didn't project low end very far. It was a ported cab and I think it was not tuned right for the drivers, or maybe was just too small.
The 1922 will be different - it won't give you port tuning problems as it's sealed, so it should be nice and tight. Will it have enough lows from the small depth (less than 12" externally)? Good question. Depends very much on your taste.
One advantage to sealed cabinets is that they don't change a ton as you change the size. Check out this diagram comparing frequency response of two sealed cabs where one has twice the internal volume of the other:
... from this article
http://www.eminence.com/2011/06/sealed-vs-ported-enclosures/If you don't have drivers handy to try the experiment, you might try playing around with some speaker cabinet design software. Feed in the cabinet dimensions and the parameters of whatever driver you're interested in and see what it predicts. For a sealed cab for 4-string, I personally would look for good response down to at least 80 hz (if it's more than 2 or 3 db down at that point I'd worry), and smooth rolloff below that.
But that takes a lot of effort for a smidgen of theoretical understanding. It might just confuse the issue. Nothing will tell you as much as your ears.